Green Synthesis of Silver Nanoparticles (CM-AgNPs) from the Root of <i>Chuanminshen</i> for Improving the Cytotoxicity Effect in Cancer Cells with Antibacterial and Antioxidant Activities.

ABSTRACT: The unique properties of silver nanoparticles (AgNPs), such as size, surface charge, and the ability to release silver ions, contribute to DNA damage, inducing of oxidative stress, and apoptosis in cancer cells. Thus, the potential application of AgNPs in the field of biomedicine, and cancer therapy are rapidly increasing day by day. Therefore, in this study, AgNPs were synthesized by extract of Chuanminshen violaceum, and then the synthesized CM-AgNPs were fully characterized. The biological activity of CM-AgNPs was investigated for antibacterial, antioxidant, and anticancer activities. The cytotoxic activity of CM-AgNPs was tested for various kinds of cancer cells including MKN45 gastric cancer cells, HCT116 human colon cancer cells, A549 human lung cancer cells, and HepG2 liver c

SUBMITTER: Wang D 

PROVIDER: S-EPMC11643779 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature