Reproductive Toxicity of Nanomaterials Using Silver Nanoparticles and <i>Drosophila</i> as Models.

ABSTRACT: Reproductive toxicity is of special concern among the harmful effects induced by environmental pollutants; consequently, further studies on such a topic are required. To avoid the use of mammalians, lower eukaryotes like Drosophila are viable alternatives. This study addresses the gap in understanding the link between reproductive adverse outcomes and the presence of pollutants in reproductive organs by using Drosophila. Silver nanoparticles (AgNPs) were selected for their ease of internalization, detection, and widespread environmental presence. Both male and female flies were exposed to AgNPs (28 ± 4 nm, 100 and 400 µg/mL) for one week. Internalization and bioaccumulation of AgNPs in organs were assessed using transmission electron microscopy, confocal microscopy, and induc

SUBMITTER: Alaraby M 

PROVIDER: S-EPMC11643907 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature