A Porcine-Derived Heme Iron Powder Restores Hemoglobin in Anemic Rats.

ABSTRACT:

Background/objectives

Iron-fortified foods reduce the incidence of iron deficiency anemia. However, the nutritional efficacy of heme iron fortificants is unclear.

Methods

In this study, we determined the hemoglobin regeneration efficiency (HRE) of a porcine-derived heme iron powder (HIP), treating anemic rats (hemoglobin (Hb) 3-6 g/dL) with 14-day repletion diets fortified with four different concentrations (12, 24, 36, or 48 mg iron/kg diets) of HIP or a control diet ("no added iron"); n = 9-12/group.

Results

Our results demonstrate an inverse association between HRE and increasing dietary iron from the HIP. The HRE ratios of diets containing the HIP powder at 12, 24, 36, or 48 mg iron/kg were 0.508, 0.268, 0.273, and 0.223, respectively. Based on the mean fin

SUBMITTER: Swain JH 

PROVIDER: S-EPMC11643988 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature