In Vitro and In Silico Biological Activities Investigation of Ethyl Acetate Extract of <i>Rubus ulmifolius</i> Schott Leaves Collected in Algeria.

ABSTRACT: This investigation aimed to assess the in vitro and in silico biological properties of the ethyl acetate (EtOAc) extract obtained from leaves of Rubus ulmifolius Schott collected in Algeria. The phytochemical screening data disclosed that flavonoids, tannins, coumarins, saponins, and anthocyanins were abundant. High levels of total phenolics, total flavonoids and flavonols (523.25 ± 3.53 µg GAE/mg, 20.41 ± 1.80, and 9.62 ± 0.51 µg QE/mg respectively) were detected. Furthermore, GC-MS analysis was performed to identify low molecular weight compounds. d-(-)-Fructofuranose, gallic acid, caffeic acid, and catechin were detected as main metabolites of the EtOAc extract. The outcomes revealed that the extract exerted a potent antioxidant apt, and ensured significant bacterial growth inhib

SUBMITTER: Bramki A 

PROVIDER: S-EPMC11644080 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature