Granulocyte-macrophage colony-stimulating factor as an immune-based therapy in HIV infection.

ABSTRACT: The HIV/AIDS epidemic continues to spread despite more than 20 years of significant research and major advances in its treatment. The introduction of highly active antiretroviral therapy in recent years has significantly improved disease treatment with a dramatic impact in HIV/AIDS associated morbidity and mortality in countries which have access to this therapy. Despite these advances, such therapies are imperfect and other therapeutic modalities, including immune-based therapies, are being actively sought. Potential benefits of immune-based therapies include: 1) the improvement of HIV-specific immunity to enhance control of viral replication, 2) the improvement of other aspects of host immunity in order to prevent or delay the development of opportunistic infections and 3) the potential

SUBMITTER: Brown PA 

PROVIDER: S-EPMC1164429 | biostudies-literature | 2005 May

REPOSITORIES: biostudies-literature