<i>Echinacea purpurea</i> and <i>Onopordum acanthium</i> Combined Extracts Cause Immunomodulatory Effects in Lipopolysaccharide-Challenged Rats.

ABSTRACT: Echinacea purpurea and Onopordum acanthium, which belong to the Asteraceae family, are widely used plants in traditional medicine. Their antioxidant, anti-inflammatory, antiviral, antibacterial, and antitumor effects are well known. However, there are no data on the effects of their combination. The aim of the present study was to combine E. purpurea with O. acanthium to study the in vivo immunomodulatory effect of two combinations and to compare it with that of single plants. Their total polyphenolic and flavonoid content and the amounts of individual compounds characteristic of both species were determined. The influence of the obtained extracts on the serum concentrations of cytokines IFN-γ, TNF-α, and IL-10 in experimental animals with lipopolysaccharide-ind

SUBMITTER: Vlasheva M 

PROVIDER: S-EPMC11644462 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature