Using In Vitro and In Silico Analysis to Investigate the Chemical Profile and Biological Properties of <i>Polygonum istanbulicum</i> Extracts.

ABSTRACT: The present study investigates the chemical profile and biological activities of Polygonum istanbulicum M. Keskin, a species endemic to Turkey, aiming to explore its potential applications in pharmacology. We assessed its phenolic and flavonoid content by employing ethyl acetate, methanol, and water as extraction solvents. The methanol extract demonstrated the highest concentrations of these compounds, with liquid chromatography-quadrupole time-of-flight tandem mass spectrometry (LC-MS-qTOF) analysis identifying a wide range of bioactive substances, such as derivatives of quercetin and myricetin. Antioxidant capacity was evaluated using 2,2-Diphenyl-1-picrylhydrazyl (DPPH), 2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS), cupric-reducing antioxidant cap

SUBMITTER: Angeles Flores G 

PROVIDER: S-EPMC11644544 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature