Effect of vitamin D status and vitamin D supplementation on immune function and prevention of acute respiratory tract infections in dark-skinned individuals: a systematic review and meta-analysis.

ABSTRACT:

Objective

This systematic review and meta-analysis examined the evidence for a potential relationship between vitamin D status and vitamin D supplementation on immune function biomarkers and prevention of acute respiratory tract infections (ARTI) in dark-skinned individuals.

Design

Six databases were searched (inception to December 2021) for randomised controlled trials (RCT) and observational studies. A narrative synthesis and random-effects meta-analysis were used to synthesise the findings.

Setting

Not applicable.

Participants

Ethnic groups other than white, with or without a white comparator.

Results

After duplicates were removed, 2077 articles were identified for screening. A total of eighteen studies (n 36 707), including seven RCT and 11 ob

SUBMITTER: Bournot AR 

PROVIDER: S-EPMC11645122 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature