Interactions Between High-Intensity Light and Unrestricted Vision in the Drive for Hyperopia.

ABSTRACT:

Purpose

To evaluate the impact of optical vs. illuminance factors and their duration-dependency on lens-induced hyperopia (LIH) in chick eyes.

Methods

Hyperopia was induced in one eye in chicks (10 groups; n = 126) from day 1 after hatching until day 8 using +10-diopter lenses with fellow eyes as controls. One group (LIH) served as the control without any interventions. The remaining groups were exposed to 2, 4, or 6 hours of unrestricted vision (UnV), high-intensity light (HL; 15,000 lux), or both (HL + UnV). Ocular axial length (AL), refractive error, and choroidal thickness were measured on days 1, 4, and 8. Inter-ocular difference (IOD = experimental - contralateral control eye) ± SEM was used to express outcome measures.

Results

By day 8, LIH decreased AL (-0.42

SUBMITTER: Biswas S 

PROVIDER: S-EPMC11645742 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature