Changes in Waveguiding Cone Photoreceptors and Color Vision in Patients With Diabetes Mellitus.

ABSTRACT:

Purpose

Although it is well known that photoreceptor damage and color vision loss occur in patients with diabetic retinopathy (DR), the relationship between structural and functional changes in diabetes mellitus (DM) remains unclear. Using highly sensitive measures of photoreceptor structure and function, we aim to determine whether early loss of color sensitivity in DM is also accompanied by decreased cone density.

Methods

Monocular data from 26 patients with DM and 25 healthy controls were examined to assess cone photoreceptor metrics, using confocal adaptive optics scanning light ophthalmoscopy, and red/green (RG) and yellow/blue (YB) color vision thresholds, using the Colour Assessment and Diagnosis test.

Results

Both RG and YB thresholds were significantly greate

SUBMITTER: Vaughan M 

PROVIDER: S-EPMC11645757 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature