Diagnostic performance of the Cobas MTB and Logix Smart MTB for diagnosing pulmonary and extrapulmonary tuberculosis: a cross-sectional study of diagnostic tests.

ABSTRACT:

Background

Molecular tests have contributed to reducing the mortality rate through early and accurate diagnosis of tuberculosis (TB). This is due to their low processing complexity and diagnostic accuracy superior to conventional methods.

Objective

To evaluate the diagnostic performance of Cobas MTB and Logix Smart MTB compared to Xpert MTB/RIF Ultra for pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB).

Design

A cross-sectional study of diagnostic tests was carried out in a clinical laboratory in Lima, Peru.

Methods

All pulmonary and extrapulmonary samples from patients with presumptive TB who had been subjected to smear microscopy, Xpert MTB/RIF Ultra, Cobas MTB, Logix Smart MTB, and mycobacteria culture were included to determine their diag

SUBMITTER: Hueda-Zavaleta M 

PROVIDER: S-EPMC11645770 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature