Molecular characterization and risk analysis of Giardia duodenalis assemblages in corticosteroid-treated and non-treated patients in Ismailia, Arab Republic of Egypt.

ABSTRACT:

Background

Giardia duodenalis (G. duodenalis) is an intestinal protozoan parasite of human and animal hosts. The present study investigated and compared the assemblages of G. duodenalis-infected faecal samples in patients on corticosteroid therapy (POCT) and control patients-not on corticosteroid therapy (CONT) and differentiated its assemblages and/or sub-assemblages' relationship with associated risk factors.

Methods

Utilizing multi-locus sequence typing (MLST) with three loci targeted-triosephosphate isomerase (tpi), ꞵ-giardin (bg), and glutamate dehydrogenase (gdh)-G. duodenalis isolated from POCT and CONT were analyzed. Risk factors linked with Giardia infection and its assemblages were investigated.

Results

In total, 52 G. duodenalis-infected patients were enrol

SUBMITTER: Ahmed SAA 

PROVIDER: S-EPMC11645789 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature