¹⁸F-FAPI-42 PET/CT enhances the diagnostic efficacy for peritoneal metastasis of colorectal cancer and guides treatment decisions: an original retrospective study.

ABSTRACT:

Background

Colorectal cancer is the third-most common type of cancer. When peritoneal metastasis (PM) develops, diagnosing metastatic lesions is difficult and the prognosis is poor. This study aimed to compare the value of fluorine-18 fibroblast activation protein-specific inhibitor (¹⁸F-FAPI-42) and fluorine-18 fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT) for detecting PM of colorectal cancer and to guide clinical decision-making.

Methods

Forty-eight patients with PM who underwent both ¹⁸F-FAPI-42 and ¹⁸F-FDG PET/CT examinations were studied. The maximum standardized uptake value (SUV max), tumor-to-background ratios (TBRs) and peritoneal cancer index (PCI) of the PM were compared between

SUBMITTER: Zhang X 

PROVIDER: S-EPMC11646066 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature