Comparative analysis of amphibian genomes: An emerging resource for basic and applied research.

ABSTRACT: Amphibians are the most threatened group of vertebrates and are in dire need of conservation intervention to ensure their continued survival. They exhibit unique features including a high diversity of reproductive strategies, permeable and specialized skin capable of producing toxins and antimicrobial compounds, multiple genetic mechanisms of sex determination and in some lineages, the ability to regenerate limbs and organs. Although genomic approaches would shed light on these unique traits and aid conservation, sequencing and assembly of amphibian genomes has lagged behind other taxa due to their comparatively large genome sizes. Fortunately, the development of long-read sequencing technologies and initiatives has led to a recent burst of new amphibian genome assemblies. Although growing

SUBMITTER: Kosch TA 

PROVIDER: S-EPMC11646304 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature