Antibiotic Resistance of Urinary Tract Infection Recurrences in a Large Integrated US Healthcare System.

ABSTRACT:

Background

Data on antibiotic resistance of uropathogens for urinary tract infection (UTI) recurrences are lacking.

Methods

In a retrospective cohort of adults at Kaiser Permanente Southern California with culture-confirmed index uncomplicated UTI (uUTI) between January 2016 and December 2020, we examined the number and characteristics of subsequent culture-confirmed UTIs through 2021.

Results

We identified 148 994 individuals with a culture-confirmed index uUTI (88% female, 44% Hispanic; mean age, 51 years [standard deviation, 19 years]), of whom 19% developed a subsequent culture-confirmed UTI after a median 300 days (interquartile range, 126-627 days). The proportion of UTI due to Escherichia coli was highest for index uUTI (79%) and decreased to 73% for sixth UTI

SUBMITTER: Ku JH 

PROVIDER: S-EPMC11646599 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature