Effects of L-carnitine supplementation on lipid profile in adult patients under hemodialysis: a systematic review and meta-analysis of RCTs.

ABSTRACT:

Background

Chronic kidney disease (CKD) affects 10% of the global population and leads to end-stage renal disease (ESRD). Hemodialysis is a common treatment for ESRD, but patients often have low carnitine levels, leading to dyslipidemia, a risk factor for cardiovascular disease and the leading cause of mortality. This study aimed to assess the effects of L-carnitine on lipid profiles in adult hemodialysis patients.

Methods

A comprehensive search was conducted across the online databases from inception to June 2024 to identify randomized clinical trials (RCTs) evaluating the effects of L-carnitine on lipid profiles in hemodialysis patients. Data extraction and quality assessment were performed, focusing on primary outcomes, including changes in triglycerides (TG), total chole

SUBMITTER: Karimi M 

PROVIDER: S-EPMC11646722 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature