Impact of extreme temperature on congenital heart disease mortality: a population-based nationwide case-crossover study.

ABSTRACT:

Background

The association between congenital heart disease (CHD) and non-optimal temperatures has received limited investigation. We aimed to investigate the impact of extreme temperatures on CHD mortality.

Methods

We reviewed the National Mortality Surveillance System of China and retrieved death records attributable to CHD from 2013 to 2021. Temperature and air pollutants data were obtained from the ERA5-Land reanalysis dataset and the ChinaHighAirPollutants database. A two-stage case-crossover study design was implemented. Sensitivity and subgroup analyses were performed to test the robustness of findings and determine the vulnerable population.

Findings

A total of 32,168 CHD deaths were included, showing a significant association between cold and CHD mortality, w

SUBMITTER: He Q 

PROVIDER: S-EPMC11646786 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature