Metabolomic heterogeneity of ageing with ethnic diversity: a step closer to healthy ageing.

ABSTRACT:

Introduction

Outside of case-control settings, ethnicity specific changes in the human metabolome are understudied especially in community dwelling, ageing men. Characterising serum for age and ethnicity specific features can enable tailored therapeutics research and improve our understanding of the interplay between age, ethnicity, and metabolism in global populations.

Objective

A metabolomics approach was adopted to profile serum metabolomes in middle-aged and elderly men of different ethnicities from the Northwest of England, UK.

Methods

Serum samples from 572 men of White European (WE), South Asian (SA), and African-Caribbean (AC) ethnicities, ranging between 40 and 86 years were analysed. A combination of liquid chromatography (LC) and gas chromatography (GC) cou

SUBMITTER: Trivedi D 

PROVIDER: S-EPMC11646956 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature