Systematic review and meta-analysis of goal-directed haemodynamic therapy algorithms during surgery for the prevention of surgical site infection.

ABSTRACT:

Background

Surgical site infection (SSI) is the most common postoperative complication. Goal-directed haemodynamic therapy (GDHT) may help to prevent SSI, but recommendations for its use initially have been set at conditional because of low-certainty evidence at the time. An updated systematic review with SSI as the primary endpoint has not been performed since 2011, and important new evidence has emerged. We assessed the influence of GDHT on SSI and other postoperative outcomes.

Methods

We searched Ovid/MEDLINE, Excerpta Medica Database (Embase.com), and Cochrane library from inception up to September 2024 for randomised controlled trials comparing the effect of any GDHT algorithm to conventional fluid therapy on SSI incidence in adult patients undergoing surgery and analys

SUBMITTER: Jalalzadeh H 

PROVIDER: S-EPMC11647171 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature