Vitamin D and/or calcium to prevent fractures and falls: protocol for a systematic review and meta-analysis.

ABSTRACT:

Background

Previous systematic reviews on fracture and fall prevention have generally shown no efficacy with calcium or vitamin D alone and conflicting findings with that of vitamin D combined with calcium. Despite these findings, increases in vitamin D and calcium prescriptions have been reported in many countries, as many clinicians, guidelines and regulatory agencies still largely recommend universal supplementation to adults.

Methods and analysis

We will conduct a systematic review of randomised controlled trials on the efficacy of vitamin D and/or calcium in fracture and fall prevention. A systematic search will be performed in Medline, Embase, CENTRAL, International Clinical Trials Registry Platform and Clinicaltrials.gov (1 January 2024). We will also hand search abst

SUBMITTER: Masse O 

PROVIDER: S-EPMC11647347 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature