Postoperative analgesic effect of intravenous coinjection of lidocaine and dexmedetomidine in gynaecological surgery: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Hysterectomy or myomectomy is a common gynaecological procedure that results in moderate to severe acute postoperative pain, which can cause many adverse effects. This study aimed to compare the postoperative analgesic efficacy, opioid consumption, quality of postoperative recovery (QOR) and adverse reactions of intravenous coinjection of lidocaine and dexmedetomidine versus lidocaine or dexmedetomidine alone in gynaecological surgery.

Design

Systematic review and meta-analysis was performed.

Data sources

The PubMed, Embase, Cochrane Library and Web of Science databases were used to access the articles. Electronic databases were searched for eligible studies published before 1 May 2024.

Eligibility criteria

All randomised controlled trials (RCTs) wer

SUBMITTER: Xie D 

PROVIDER: S-EPMC11647388 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature