Advancement in predictive biomarkers for gestational diabetes mellitus diagnosis and related outcomes: a scoping review.

ABSTRACT:

Objective

Gestational diabetes mellitus (GDM) is a metabolic disorder associated with adverse maternal and neonatal outcomes. While GDM is diagnosed by oral glucose tolerance testing between 24-28 weeks, earlier prediction of risk of developing GDM via circulating biomarkers has the potential to risk-stratify women and implement targeted risk reduction before adverse obstetric outcomes. This scoping review aims to collate biomarkers associated with GDM development, associated perinatal outcome and medication requirement in GDM.

Design

The Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for scoping reviews was used to guide the study.

Data sources

This review searched for articles on PubMed, Embase, Scopus, Cochrane Central Register of Cont

SUBMITTER: Rathnayake H 

PROVIDER: S-EPMC11647389 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature