Synergistic air pollution exposure elevates depression risk: A cohort study.

ABSTRACT: Depression is a leading mental health disorder worldwide, contributing substantially to the global disease burden. While emerging evidence suggests links between specific air pollutants and depression, the potential interactions among multiple pollutants remain underexplored. Here we show the influence of six common air pollutants on depressive symptoms among middle-aged and older Chinese adults. In single-pollutant models, a 10 μg m^-3 increase in SO₂, CO, PM₁₀, and PM_2.5 is associated with increased risks of depressive symptoms, with odds ratios (95% confidence intervals) of 1.276 (1.238-1.315), 1.007 (1.006-1.008), 1.066 (1.055-1.078), and 1.130 (1.108-1.153), respectively. In two-pollutant models, SO₂ remains significantly associate

SUBMITTER: Hao Y 

PROVIDER: S-EPMC11647501 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature