Cross-Sectional and Prospective Associations between Parkinsonism and Parkinson's Disease with Frailty in Latin America.

ABSTRACT:

Background

Little is known about the relationship between parkinsonism or Parkinson's disease (PD) and frailty in Latin America.

Objective

The study aimed to determine the cross-sectional and prospective associations between parkinsonism and PD with frailty in a large multi-country cohort in Latin America. Frailty was assessed using three different models to explore which definitions are more appropriate to screen for frailty in a PD population.

Methods

12,865 older adults (aged ≥65 years) from the 10/66 population-based cohort study in six Latin American countries were analyzed. Logistic regression models assessed the cross-sectional association between parkinsonism/PD with baseline frailty. Individual country analyses were combined via fixed-effect meta-analysis. In

SUBMITTER: Kim DJ 

PROVIDER: S-EPMC11648000 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature