Predictors of poor treatment outcomes among drug-resistant tuberculosis patients in Hunan province, China.

ABSTRACT:

Background

Drug-resistant tuberculosis (DR-TB) is a significant public health concern, often resulting in poor treatment outcomes. This study aims to identify predictors of poor treatment outcomes among patients with DR-TB in Hunan Province, China.

Methods

A retrospective cohort study was conducted in Hunan Province using data collected between 2013 and 2018 among patients with DR-TB treatment. Univariable and multivariable parametric survival analyses were performed using a shared frailty survival model with a Weibull distribution and Gamma frailty to identify determinants of poor treatment outcomes. Adjusted hazard ratios (AHR) with a 95 % confidence interval (CI) were calculated for the best-fitted model. The goodness of fit for the model was assessed using the Cox-Snell

SUBMITTER: Akalu TY 

PROVIDER: S-EPMC11648092 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature