Optic disc changes in Chinese patients with <i>NLRP3</i>-associated autoinflammatory disease.

ABSTRACT:

Objective

To investigate the optic disc changes (ODC) in Chinese patients with NLRP3-associated autoinflammatory disease (NLRP3-AID).

Methods

Patients who were diagnosed with NLRP3-AID at the Department of Rheumatology, Peking Union Medical College Hospital between April 2015 and December 2022 were retrospectively reviewed and analyzed.

Results

A total of 20 patients were enrolled in this retrospective study. All 20 patients had a moderate MWS NLRP3-AID phenotype. Thirteen patients (65%) had ocular involvements. The interval between symptoms onset and diagnosis was significantly longer in patients with ocular involvement than in patients without (p = 0.044). The incidence of hearing loss was significantly higher in patients with ocul

SUBMITTER: Lu Y 

PROVIDER: S-EPMC11648131 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature