ELemur: A cellular-resolution 3D atlas of the mouse lemur brain.

ABSTRACT: The gray mouse lemur (Microcebus murinus), one of the smallest living primates, emerges as a promising model organism for neuroscience research. This is due to its genetic similarity to humans, its evolutionary position between rodents and humans, and its primate-like features encapsulated within a rodent-sized brain. Despite its potential, the absence of a comprehensive reference brain atlas impedes the progress of research endeavors in this species, particularly at the microscopic level. Existing references have largely been confined to the macroscopic scale, lacking detailed anatomical information. Here, we present eLemur, a unique resource, comprising a repository of high-resolution brain-wide images immunostained with multiple cell type and structural markers, elucidating the c

SUBMITTER: Jeon H 

PROVIDER: S-EPMC11648901 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature