Microstructural asymmetries of the planum temporale predict functional lateralization of auditory-language processing.

ABSTRACT: Structural hemispheric asymmetry has long been assumed to guide functional lateralization of the human brain, but empirical evidence for this compelling hypothesis remains scarce. Recently, it has been suggested that microstructural asymmetries may be more relevant to functional lateralization than macrostructural asymmetries. To investigate the link between microstructure and function, we analyzed multimodal MRI data in 907 right-handed participants. We quantified structural asymmetry and functional lateralization of the planum temporale (PT), a cortical area crucial for auditory-language processing. We found associations between PT functional lateralization and several structural asymmetries, such as surface area, intracortical myelin content, neurite density, and neurite orientation dis

SUBMITTER: Qin P 

PROVIDER: S-EPMC11649236 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature