Association of metalloestrogens exposure with depression in women across reproductive lifespan.

ABSTRACT:

Background

Exposure to metal could impact women's depression risk. However, the connection and mechanisms between metalloestrogens exposure and depression are still not fully understood. We aim to explore the associations between metalloestrogens and the risk of depression in women across reproductive lifespan.

Methods

Using data from NHANES 2011-2018, we employed logistic regression and baknernel machine regression (BKMR) to study links between metalloestrogen exposure and depression in US women. We analyzed how contraceptive use affects this relationship.

Results

The study involved 3,374 adult women, with 345 of them experiencing depression. Our research revealed that certain metalloestrogens like Ba, Ca, Pb, Sb, and Sn were linked to higher depression risk in women

SUBMITTER: Ren J 

PROVIDER: S-EPMC11649658 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature