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Occupational performance patterns in children with paediatric acute-onset neuropsychiatric syndrome.


ABSTRACT:

Introduction

Paediatric acute-onset neuropsychiatric syndrome (PANS) is a neuroimmune condition characterised by episodic exacerbations and remissions. This study investigates the impact of PANS on children's occupational performance during these phases, using the Vineland Adaptive Behaviour Scale (VABS). Understanding these variations is crucial for developing tailored interventions and managing the condition effectively.

Methods

A two-period bidirectional case-crossover design was employed to assess occupational performance in children with PANS at exacerbation (T-E) and remission (T-R) phases. Parents of children aged 4.6-13.1 years with PANS were recruited globally, with data collected via online surveys and monthly updates. The VABS evaluated occupational performance, w

SUBMITTER: Newby MJ 

PROVIDER: S-EPMC11650011 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature