Conceptual basis for the development of guidance for the use of biomarkers of effect in regulatory risk assessment of chemicals.

ABSTRACT: This Scientific Report was carried out in the context of the self-task mandate (M-2023-00097) of the EFSA's Scientific Committee on 'Guidance on the use of biomarkers of effect in regulatory risk assessment of chemicals'. In the first phase, the project on biomarkers of effect started with a feasibility study (EFSA-Q-2024-00128), with the intention to look closer at definitions and descriptions of biomarkers of effect, as well as to explore several concepts related to the context of application and other scientific principles to be further considered for its development. In addition, relevant activities, initiatives and knowledge in this area were collected and analysed within a complementary mapping study. The outcome of this phase aimed to create a structured basis for future guidance, t

SUBMITTER: European Food Safety Authority (EFSA) 

PROVIDER: S-EPMC11650060 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature