Cannabis use and cognitive biases in people with first-episode psychosis and their siblings.

ABSTRACT:

Background

Cannabis use and familial vulnerability to psychosis have been associated with social cognition deficits. This study examined the potential relationship between cannabis use and cognitive biases underlying social cognition and functioning in patients with first episode psychosis (FEP), their siblings, and controls.

Methods

We analyzed a sample of 543 participants with FEP, 203 siblings, and 1168 controls from the EU-GEI study using a correlational design. We used logistic regression analyses to examine the influence of clinical group, lifetime cannabis use frequency, and potency of cannabis use on cognitive biases, accounting for demographic and cognitive variables.

Results

FEP patients showed increased odds of facial recognition processing (FRP) deficits (

SUBMITTER: Roldan L 

PROVIDER: S-EPMC11650177 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature