Fractal motor activity during wakefulness and sleep: a window into depression recency and symptom recurrence.

ABSTRACT:

Background

Motor activity fluctuations in healthy adults exhibit fractal patterns characterized by consistent temporal correlations across wide-ranging time scales. However, these patterns are disrupted by aging and psychiatric conditions. This study aims to investigate how fractal patterns vary across the sleep-wake cycle, differ based on individuals' recency of depression diagnosis, and change before and after a depressive episode.

Methods

Using actigraphy from two cohorts (n = 378), we examined fractal motor activity patterns both between individuals without depression and with varying recencies of depression and within individuals before and after depressive symptom recurrence. To evaluate fractal patterns, we quantified temporal correlations in motor activity flu

SUBMITTER: Minaeva O 

PROVIDER: S-EPMC11650180 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature