Adverse psychiatric effects of psychedelic drugs: a systematic review of case reports.

ABSTRACT:

Background

Psychedelic drugs are a focus of interest in the treatment of depression and other disorders but there are longstanding concerns about possible adverse psychiatric consequences. Because the relevant literature is largely informal, the seriousness of these risks is difficult to evaluate.

Methods

Searches were made for case reports of schizophrenia-spectrum, affective or other psychiatric disorders after use of psychedelic drugs. Case reports of flashbacks were also searched for. Individuals with recent use of other drugs (apart from cannabis and alcohol) and/or a previous history of major psychiatric disorder were excluded. Symptoms were tabulated using the Syndrome Check List of the Present State Examination (PSE-9).

Results

We found 17 case reports of schi

SUBMITTER: Yildirim B 

PROVIDER: S-EPMC11650183 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature