Associations among environmental unpredictability, changes in resting-state functional connectivity, and adolescent psychopathology in the ABCD study.

ABSTRACT:

Background

Unpredictability is a core but understudied dimension of adversities and has been receiving increasing attention recently. The effects of unpredictability on psychopathology and the underlying neural mechanisms, however, remain unclear. It is also unknown how unpredictability interacts with other dimensions of adversities in predicting brain development and psychopathology of youth.

Methods

We applied cluster robust standard errors to examine how unpredictability was associated with the developmental changes in resting-state functional connectivity (rsFC) of large-scale brain networks implicated in psychopathology, as well as the moderating role of deprivation, using data from the Adolescent Brain Cognitive Development (ABCD) study, which included four measurement

SUBMITTER: Yang Y 

PROVIDER: S-EPMC11650185 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature