Malignant transformation of nephrogenic adenoma of the bladder: case report and literature review.

ABSTRACT:

Background

Nephrogenic adenoma (NA) is a rare benign tumor that can develop at any site of the urinary system, with the bladder being the most common, followed by the urethra, ureters, renal pelvises, etc. Currently, it is unclear what the pathogenesis of NA is. This study discussed a rare case of malignant transformation from NA to mesonephric adenocarcinoma of the bladder.

Case description

A 66-year-old man with a bladder mass was admitted to the hospital. A cystoscopic electro biopsy and transurethral resection of bladder tumor (TUR-BT) pathologically indicated that the patient had an NA of the bladder. Furthermore, immunohistochemistry analysis revealed: Pax-8 (+), Pax-2 (-), CK7 (+), EMA (+), p63 (a small proportion+), Ki-67 (1%+). The patient underwent a robot-assisted

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11650344 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature