Coronary Microvascular Dysfunction Years After Cessation of Anabolic Androgenic Steroid Use.

ABSTRACT:

Importance

Long-term use of anabolic androgenic steroids (AASs) is associated with a high risk of left ventricular hypertrophy, heart failure with reduced systolic function, and early sudden death, with the mechanism of progression being understudied. Early and persistent impaired myocardial microcirculation could be of clinical importance and a potential underlying mechanism of frequent and early cardiac disease among individuals with AAS use and a future potential target for intervention.

Objective

To investigate coronary microcirculation by measuring myocardial flow reserve (MFR) in men with current and former AAS use compared with controls with no prior AAS use, using cardiac rubidium 82 (82Rb) positron emission tomography/computed tomography (PET/CT).

Design, setting

SUBMITTER: Bulut Y 

PROVIDER: S-EPMC11650407 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature