Transcutaneous Auricular Vagus Nerve Stimulation for Chronic Insomnia Disorder: A Randomized Clinical Trial.

ABSTRACT:

Importance

Evidence from randomized clinical trials of transcutaneous auricular vagus nerve stimulation (taVNS) for chronic insomnia disorder is lacking.

Objective

To evaluate the efficacy and safety of taVNS for chronic insomnia compared with the sham taVNS.

Design, setting, and participants

This randomized clinical trial was conducted from October 2021 to December 2022 at a single center in Beijing, China. Patients with chronic insomnia disorder with a Pittsburgh Sleep Quality Index (PSQI) of at least 8 were enrolled. Statistical analysis was performed from June to September 2023.

Interventions

Patients were allocated to the active taVNS group or sham taVNS group with a 1:1 ratio. Both groups received the stimulation for 30 minutes each time, twice a day, 5 c

SUBMITTER: Zhang S 

PROVIDER: S-EPMC11650411 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature