Performance of urinary C-C motif chemokine ligand 14 and the renal resistive index in predicting persistent AKI.

ABSTRACT:

Objectives

The purpose of this study was to evaluate the performance of urinary C-C motif chemokine ligand 14 (CCL14) and the renal resistive index (RI) in predicting persistent AKI in unselected critically ill patients.

Methods

This prospective observational study was conducted in a tertiary hospital's general intensive care unit (ICU). Consecutive adults who were admitted to the ICU were enrolled, with a primary endpoint of AKI lasting 48 h or longer. Urinary CCL14 was evaluated upon inclusion, and the renal RI was determined within 12 h of ICU admission. The individual discriminative ability of urinary CCL14 and the renal RI to predict persistent AKI was evaluated by the area under the receiver operating characteristic curve (AUC).

Results

Overall, 166 patients wer

SUBMITTER: Fu Y 

PROVIDER: S-EPMC11650427 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature