The prognostic value of [¹⁸F]FDG PET/CT texture analysis prior to transplantation for unresectable colorectal liver metastases.

ABSTRACT:

Introduction

To determine whether heterogeneity in colorectal liver metastases (CRLM) ¹⁸F fluorodeoxyglucose [¹⁸F]FDG distribution is predictive of disease-free survival (DFS) and overall survival (OS) following liver transplantation (LT) for unresectable CRLM.

Methods

The preoperative [¹⁸F]FDG positron emission tomography/computed tomography examinations of all patients in the secondary cancer 1 and 2 studies were retrospectively assessed. Maximum standardized uptake value (SUV_max), metabolic tumour volume (MTV), and six texture heterogeneity parameters (joint entropy_GLCM, dissimilarity_GLCM, grey level variance_SZM, size zone variance_SZM, and zone percentage_SZM, and morphologic

SUBMITTER: Stern NM 

PROVIDER: S-EPMC11650445 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature