Reducing thermal noise in high-resolution quantitative magnetic resonance imaging rotating frame relaxation mapping of the human brain at 3 T.

ABSTRACT: Quantitative maps of rotating frame relaxation (RFR) time constants are sensitive and useful magnetic resonance imaging tools with which to evaluate tissue integrity in vivo. However, to date, only moderate image resolutions of 1.6 x 1.6 x 3.6 mm³ have been used for whole-brain coverage RFR mapping in humans at 3 T. For more precise morphometrical examinations, higher spatial resolutions are desirable. Towards achieving the long-term goal of increasing the spatial resolution of RFR mapping without increasing scan times, we explore the use of the recently introduced Transform domain NOise Reduction with DIstribution Corrected principal component analysis (T-NORDIC) algorithm for thermal noise reduction. RFR acquisitions at 3 T were obtained from eight healthy participants (seven

SUBMITTER: Ponticorvo S 

PROVIDER: S-EPMC11650668 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature