Psychotic relapse prediction via biomarker monitoring: a systematic review.

ABSTRACT:

Background

Associating temporal variation of biomarkers with the onset of psychotic relapse could help demystify the pathogenesis of psychosis as a pathological brain state, while allowing for timely intervention, thus ameliorating clinical outcome. In this systematic review, we evaluated the predictive accuracy of a broad spectrum of biomarkers for psychotic relapse. We also underline methodological concerns, focusing on the value of prospective studies for relapse onset estimation.

Methods

Following the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines, a list of search strings related to biomarkers and relapse was assimilated and run against the PubMed and Scopus databases, yielding a total of 808 unique records. After exclusion of stud

SUBMITTER: Smyrnis A 

PROVIDER: S-EPMC11650710 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature