Changes in allele frequencies and genetic architecture due to selection in two pig populations.

ABSTRACT:

Background

Genetic selection improves a population by increasing the frequency of favorable alleles. Understanding and monitoring allele frequency changes is, therefore, important to obtain more insight into the long-term effects of selection. This study aimed to investigate changes in allele frequencies and in results of genome-wide association studies (GWAS), and how those two are related to each other. This was studied in two maternal pig lines where selection was based on a broad selection index. Genotypes and phenotypes were available from 2015 to 2021.

Results

Several large changes in allele frequencies over the years were observed in both lines. The largest allele frequency changes were not larger than expected under drift based on gene dropping simulations, but the a

SUBMITTER: Wientjes YCJ 

PROVIDER: S-EPMC11650847 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature