Evaluating post-thrombectomy effective connectivity changes in anterior circulation stroke.

ABSTRACT:

Objective

Granger causal analysis (GCA) and amplitude of low-frequency fluctuation (ALFF) are commonly used to evaluate functional alterations in brain disorders. By combining the GCA and ALFF, this study aimed to investigate the effective connectivity (EC) changes in patients with acute ischemic stroke (AIS) and anterior circulation occlusion after mechanical thrombectomy (MT).

Methods

Resting-state functional magnetic resonance imaging (rs-fMRI) data were collected from 43 AIS patients with anterior circulation occlusion within 1 week post-MT and 37 healthy controls. ALFF and GCA were calculated for each participant. Patients were further divided into groups based on prognosis and perfusion levels. The differences in ALFF and EC were compared between AIS patients and healt

SUBMITTER: Xu J 

PROVIDER: S-EPMC11651213 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature