Immunotherapy for locally advanced and metastatic basal cell carcinoma: a narrative review.

ABSTRACT:

Background and objective

Basal cell carcinoma (BCC) is the most common malignancy of humankind, characterized by its low propensity for metastasis and its high recurrence rate. Surgical intervention is the predominant therapeutic approach. However, for cases of locally advanced BCC (laBCC) and metastatic BCC (mBCC), systematic therapy may be the first option. In recent years, tumor immunotherapy has garnered significant attention within the scientific community. And it has progressively demonstrated its efficacy in the treatment of laBCC and mBCC. This review aims to summarize the characteristics of immune microenvironment, biomarkers, and immunotherapies of BCC, and provide a reference for further research on BCC immunotherapy.

Methods

We searched literature in PubMed datab

SUBMITTER: Li X 

PROVIDER: S-EPMC11651781 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature