A narrative clinical trials review in the realm of focal therapy for localized prostate cancer.

ABSTRACT:

Background and objective

The role of focal therapy in the treatment of localized prostate cancer is evolving. However, despite accumulating evidence, current guidelines and regulatory bodies refrain from endorsing focal therapy outside of clinical trials. Our goal was the to review the focal therapy realm for ongoing clinical trials and high impact recently published trials.

Methods

Our comprehensive investigation includes an exhaustive review of ClinicalTrials.gov and PubMed databases, identifying and analyzing clinical trials with diverse modalities of focal therapy. In this review, we focused on critical ongoing and recently concluded clinical trials (2-15-2023) in the focal therapy realm.

Key content and findings

We identified several trials on focal therapy at va

SUBMITTER: Lazarovich A 

PROVIDER: S-EPMC11651783 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature