Assessing regional homogeneity and cognitive function alterations in pediatric brain tumor patients: a resting-state functional magnetic resonance imaging study.

ABSTRACT:

Background

Cognitive impairment mechanisms in children with preoperative brain tumors are not well understood. This study aimed to determine the correlation between the changes of resting-state functional magnetic resonance imaging (rs-fMRI) and the fourth edition of the Wechsler Intelligence Scale for Children (WISC-IV) in patients with brain tumors before surgery and in healthy controls (HCs).

Methods

rs-fMRI data were acquired using 3-T magnetic resonance imaging (MRI) scanners for 21 patients with pediatric brain tumor and 19 age- and gender-matched HCs. The data of WISC-IV were collected by psychiatrists. We used chi-square tests and two-sample t-tests to identify clinical features with significant associations before surgery. A two-sample t-tests was used to ide

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC11651996 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature