Comparison of normalized cerebral blood flow between different post-processing methods of dynamic susceptibility contrast perfusion-weighted imaging and arterial spin labeling in gliomas with different grading.

ABSTRACT:

Background

Two post-processing methods of dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI), arterial input function (AIF) and gamma-variate fitting (GVF), can both derive cerebral blood flow (CBF). Moreover, AIF can provide T2* and T1 leakage indicators. This study aimed to compare the consistency of normalized CBF between different post-processing methods of DSC-PWI and arterial spin labeling (ASL) in gliomas, and take the quantitative metrics percentage of signal recovery (PSR) as a reference to verify the value of T2* and T1 leakage indicators in characterizing leakage effect and evaluating the grading of gliomas.

Methods

From 1 January 2020 to 15 December 2023, 56 consecutive inpatients were retrospectively enrolled, comprising 24 patients with low-gr

SUBMITTER: Wang C 

PROVIDER: S-EPMC11652009 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature