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Challenges in magnetic resonance imaging-based detection of clinically significant prostate cancer in young patients: two alternative approaches.


ABSTRACT:

Background

Addition of magnetic resonance imaging (MRI) in prostate cancer screening remains controversial issue. Despite the increased utilization of MRI, several studies have revealed its potential suboptimal diagnostic efficacy in young patients. This study aimed to further substantiate the limited diagnostic efficiency of MRI positivity [defined as Prostate Imaging Reporting and Data System (PI-RADS) scores ≥3] among young individuals aged ≤55 years suspected of prostate cancer, and more significantly, to evaluate two proposed approaches.

Methods

A total of 2,599 patients (including 207 young patients) who underwent trans-perineal prostate biopsy between January 2019 and May 2023 were included in this study. Categorical variables were compared using the chi-square or Fis

SUBMITTER: Huang TB 

PROVIDER: S-EPMC11652039 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature