Evaluating the efficacy of low-kV X-ray intraoperative radiotherapy in the treatment of locally advanced rectal cancer: a retrospective cohort study.

ABSTRACT:

Background

Patients with locally advanced rectal cancer (LARC) treated with surgery have a high risk of local recurrence. Intraoperative radiotherapy (IORT) is a promising method for treating locally advanced solid tumors, but there is limited research on the efficacy of IORT in treating LARC. This study aimed to evaluate the long-term efficacy of low-kV X-ray IORT in the treatment of LARC.

Methods

In total, 69 LARC patients with stage tumor_3-4node_0-2metastasis₀ (T_3-4N_0-2M₀) treated with radical resection and low-kV X-ray IORT at our center from December 2015 to August 2023 were consecutively included in this retrospective cohort study. Basic patient characteristics, intraoperative and postoperative data, and

SUBMITTER: Li J 

PROVIDER: S-EPMC11652056 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature